If they are implemented correctly then the short answer is yes. The use of a popup ad as a marketing strategy is still today alive a well however, the delivery methods have changed considerably over the years.
Getresponse
Choosing Your Autoresponder Service
If you need a simple autoresponder which must be able to do the basics like sending preset messages to the persons who e-mailed you, then search for a free autoresponder or you can simply set this simple task up using you web hosts email program.

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